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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: EPS8L2 All Species: 19.7
Human Site: T59 Identified Species: 61.9
UniProt: Q9H6S3 Number Species: 7
    Phosphosite Substitution
    Charge Score: -0.14
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q9H6S3 NP_073609.2 715 80621 T59 Y H V Q H L A T F I M D K S E
Chimpanzee Pan troglodytes XP_512904 745 82543 T78 Y P V N H L V T F C L G E D D
Rhesus Macaque Macaca mulatta XP_001116697 615 68955 T59 Y H V Q H L A T F I M D K S E
Dog Lupus familis XP_534881 791 88639 K67 K L K L L D A K G K V W T Q D
Cat Felis silvestris
Mouse Mus musculus Q99K30 729 82211 T59 Y H V Q H L A T F I M D K S E
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510664 556 62861
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_002666818 677 76506 T60 Y H V Q H L S T F V M D K T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_785396 970 107261 T184 F P V E H L Y T F A M D K K E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 42.2 79.7 42.5 N.A. 84 N.A. N.A. 29 N.A. N.A. 56.5 N.A. N.A. N.A. N.A. 24.6
Protein Similarity: 100 58.2 80.8 60.1 N.A. 90.1 N.A. N.A. 46.1 N.A. N.A. 70.7 N.A. N.A. N.A. N.A. 40.5
P-Site Identity: 100 40 100 6.6 N.A. 100 N.A. N.A. 0 N.A. N.A. 80 N.A. N.A. N.A. N.A. 60
P-Site Similarity: 100 60 100 20 N.A. 100 N.A. N.A. 0 N.A. N.A. 100 N.A. N.A. N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 50 0 0 13 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 13 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 13 0 0 0 0 0 63 0 13 25 % D
% Glu: 0 0 0 13 0 0 0 0 0 0 0 0 13 0 63 % E
% Phe: 13 0 0 0 0 0 0 0 75 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 13 0 0 13 0 0 0 % G
% His: 0 50 0 0 75 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 38 0 0 0 0 0 % I
% Lys: 13 0 13 0 0 0 0 13 0 13 0 0 63 13 0 % K
% Leu: 0 13 0 13 13 75 0 0 0 0 13 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 63 0 0 0 0 % M
% Asn: 0 0 0 13 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 25 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 50 0 0 0 0 0 0 0 0 0 13 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 13 0 0 0 0 0 0 38 0 % S
% Thr: 0 0 0 0 0 0 0 75 0 0 0 0 13 13 0 % T
% Val: 0 0 75 0 0 0 13 0 0 13 13 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 13 0 0 0 % W
% Tyr: 63 0 0 0 0 0 13 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _